Diagnostic value of tumor biomarkers CA125 and CA72-4 in differentiation of epithelial ovarian cancer and endometrioma
نویسندگان
چکیده
منابع مشابه
The use of HE4, CA125 and CA72-4 biomarkers for differential diagnosis between ovarian endometrioma and epithelial ovarian cancer
BACKGROUND Endometriosis is frequently associated with high levels of CA125. This marker is therefore not useful for discriminating ovarian endometrioma from ovarian malignancy. The aim of this study was to establish a panel of complementary biomarkers that could be helpful in the differential diagnosis between ovarian endometriosis or other ovarian benign masses and ovarian cancer. METHODS B...
متن کاملIs CA72-4 a Useful Biomarker in Differential Diagnosis between Ovarian Endometrioma and Epithelial Ovarian Cancer?
BACKGROUND Surgical excision of ovarian endometriomas in patients desiring pregnancy has recently been criticized because of the risk of damage to healthy ovarian tissue and consequent reduction of ovarian reserve. A correct diagnosis in cases not scheduled for surgery is therefore mandatory in order to avoid unexpected ovarian cancer misdiagnosis. Endometriosis is often associated with high le...
متن کاملThe Value of CA 125 and CA72-4 in Management of Patients with Epithelial Ovarian Cancer
UNLABELLED The role of the tumor markers CA125 and CA72-4 has been evaluated in the diagnosis and management of ovarian cancer. Both markers were measured in 30 patients with proven epithelial ovarian cancer, 30 patients with benign pelvic masses and 30 normal women. CA125 and CA72-4 were measured using the luminometric immunoassay and immunoradiometric assay respectively. All patients with ova...
متن کاملComparing the Diagnostic Value of the Risk of Ovarian Malignancy Algorithm and CA125 in Patients with Ovarian Mass
Background and purpose: Ovarian cancer is the fourth leading cause of death from gynecological cancers in women. Using specific tumor markers that help in making diagnosis at early stages improve therapeutic outcomes. The purpose of this study was to evaluate the diagnostic value of the Risk of Ovarian Malignancy Algorithm (ROMA) index in patients with ovarian mass. Materials and methods: A cr...
متن کاملCorrelation of Preoperative HE-4 and CA125 with Ovarian Cancer Staging in Ahvaz Imam Khomeni Hospital
Background: Given that ovarian cancer symptoms are nonspecific and that appropriate surgical staging and pathological grading are important for the best treatment and prognosis of patients, this study aimed to determine the correlation of preoperative serum levels of CA125 and He4 with staging and grading. Materials and Methods: This cross-sectional study recruited 29 patients with epithelial...
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ژورنال
عنوان ژورنال: Biomedical Research
سال: 2018
ISSN: 0976-1683
DOI: 10.4066/biomedicalresearch.29-18-114